Collagen supplementation may help control blood sugar levels: Study

Researchers observed that the collagen group recorded an average 0.3% drop in HbA1c levels, a clinically relevant indicator in long-term glucose control

By Anoushka Caroline Williams
Published on : 12 July 2025 3:00 PM IST

Collagen supplementation may help control blood sugar levels: Study

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Hyderabad: India has one of the world’s largest populations of Type 2 diabetes patients, with diet and lifestyle playing a crucial role in disease management.

However, collagen, a structural protein gaining popularity for its potential health benefits, is not a common component of the traditional Indian diet.

Now, a new study suggests that collagen supplementation might have a positive impact on blood sugar control, sparking interest among clinicians and nutritionists about its potential role in diabetes care.

New Study Links Collagen with Improved Glucose Control

Published in Diabetes & Metabolism Research, the study followed 1,200 adults with prediabetes and early-stage Type 2 diabetes over 18 months. Participants who consumed hydrolysed collagen peptides daily experienced consistent improvements in fasting blood glucose levels and insulin sensitivity compared to those who didn’t.

Researchers observed that the collagen group recorded an average 0.3% drop in HbA1c levels, a clinically relevant indicator in long-term glucose control.

ā€œWhile collagen is not a substitute for conventional diabetes medications, these findings suggest it may have adjunctive benefits, particularly through its influence on gut health and inflammation,ā€ said Dr. Meena Iyer, a clinical endocrinologist.

How Collagen May Influence Metabolic Health

Collagen’s potential role in glucose regulation is believed to stem from a combination of factors:

• Amino Acid Composition: Collagen is rich in glycine, proline, and hydroxyproline — amino acids that may support insulin function and reduce systemic inflammation.

• Impact on Gut Health: There is emerging evidence that collagen supplements may help maintain gut lining integrity and promote beneficial microbiota, both of which affect metabolism.

• Satiety and Weight Control: As a protein supplement, collagen may enhance satiety and reduce calorie intake, an indirect benefit for those managing blood sugar levels.

ā€œAny nutritional intervention that improves gut integrity and reduces inflammation could indirectly support glycaemic control,ā€ noted Dr. Pranita Gokhale, a metabolic nutrition researcher.

Should People with Diabetes Take Collagen?

Experts caution that while the early findings are promising, collagen is not a standalone treatment and should not be considered a replacement for prescribed diabetes therapies.

ā€œPeople with diabetes are increasingly turning to supplements, but they need to remember that evidence is still evolving. It’s best to consult your doctor or dietitian before adding collagen to your routine,ā€ said Dr. Iyer.

Though generally safe, collagen supplements may not be suitable for everyone, particularly those with kidney issues or protein restrictions.

The Indian Context: Access, Acceptance, and Alternatives

Despite growing interest globally, collagen is not traditionally consumed in most Indian households. Most commercially available collagen supplements in India are derived from bovine or marine sources, which may not align with vegetarian diets or certain religious preferences.

ā€œIn India, where large sections of the population avoid animal-based products, the uptake of collagen supplements remains limited,ā€ said Dr. Gokhale.

However, several plant-based foods are believed to support natural collagen synthesis, including amla (Indian gooseberry), sesame seeds, aloe vera, and vitamin C-rich fruits. These may offer a culturally acceptable route to supporting similar benefits, though more research is needed.

What’s Next for Research

Experts agree that the study represents a positive step in understanding nutritional strategies for managing Type 2 diabetes, but emphasize the need for more data.

ā€œIt’s a good first step, but we need broader studies involving diverse populations and well-defined clinical endpoints,ā€ said Dr. Shashi Patel, a diabetes researcher.

Further investigation is also required to compare different forms of collagen, such as peptides vs. whole protein vs. dietary sources, and their long-term impacts.

Final Takeaway

While collagen may offer supportive benefits for people managing Type 2 diabetes, especially through its effects on gut health, inflammation, and satiety, it is not a cure or primary treatment. For Indian patients, especially, dietary compatibility and cultural preferences must be considered before supplementation.

Experts recommend sticking to a holistic approach, involving proper medical care, dietary regulation, physical activity, and regular monitoring, while exploring supportive nutritional tools like collagen only under professional guidance.

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