Hyd CCMB-led NCBS conducting genome sequencing to detect Omicron variant

Two Omicron cases have been reported in Karnataka, there genome sequencing was done at the National Centre for Biological Sciences (NCBS).

By Newsmeter Network  Published on  3 Dec 2021 12:35 PM GMT
Hyd CCMB-led NCBS conducting genome sequencing to detect Omicron variant

Hyderabad: The Union health ministry on Thursday confirmed that two Omicron cases have been reported in Karnataka. The genome sequencing was done at the National Centre for Biological Sciences (NCBS) that confirmed the first two cases of the Omicron variant in Bangalore on Thursday.

NCBS is part of a consortium of national laboratories performing genomic surveillance across four city clusters – Bangalore, Hyderabad, New Delhi, and Pune.

The consortium was established four months ago with support from the Rockefeller Foundation's Pandemic Prevention Institute and is led by the Centre for Cellular and Molecular Biology (CCMB) in Hyderabad.

The consortium is focused on upscaling genomic surveillance as part of national efforts led by the INSACOG (Indian SARS-CoV-2 Genomics Consortium) to respond to the COVID-19 pandemic. The consortium intensified its sequencing efforts after the World Health Organization announced Omicron as a Variant of Concern.

Such an intensified effort enabled the Bangalore team at the NCBS, a member laboratory of INSACOG, in collaboration with Strand Life Sciences and the Bruhat Bengaluru Mahanagara Palike (BBMP), to detect, rapidly sequence, and verify the existence of the Omicron variant in samples from two COVID-19 infected individuals.

They hope this will aid in a rapid response to contain the spread of variants of concern. Prof. Satyajit Mayor from NCBS conveyed the information to local and national authorities and the Indian government released a statement on 2 December afternoon, all within four days of receiving the samples. Both SARS-CoV-2 genomes have also been uploaded to the global repository for SARS-CoV-2 sequences, GISAID, so that they can be publicly available to the scientific community.

Dr. Rakesh Mishra at the CCMB said the consortium is continuously monitoring the situation in all four cities and has upscaled its efforts to sequence as many samples as possible.

Apart from the CCMB and the NCBS, the consortium includes the CSIR-Institute of Genomics and Integrative Biology - IGIB in New Delhi and the Pune Knowledge Cluster, Indian Institute of Science Education and Research (IISER), Pune, and CSIR-National Chemical Laboratory in Pune.

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